To date,atherosclerosis has been considered as an inflammatory process triggered by diverse immune cells.The cells involved in innate immunity such as monocytes and macrophages,adaptive immunity such as T cells and B cells,and cytokines secreted by immune cells all participate in the process.However,the cells involved functions differently with some promoting atherosclerosis while others inhibiting it.In human,CD14+CD16+was pro-inflammatory,whereas CD14+CD16-was anti-inflammatory.Th1and Th17 cells have a pro-atherogenic role,while Th2 and CD4+CD25+ regulatory T cells act oppositely.In recent years,antibodies targeting oxLDL were proven athero-protective in studies.It is no doubt that a further understanding of immunological mechanisms in atherosclerosis will guide effective prevention and therapeutics of this disorder.