Aim To investigate temporary core venous cannula hemodialysis patient's pipe related complication and its relationship with time and position of pipe incubation. Methods Collect 753 patients with core venous cannula hemodialysis,analyze risk factors correlated with hemodialysis patient's pipe related complication,investigate incubation time and position's impact on pipe related complication. Results The locatong of deep venous intubation,resistant time are both relevant to catheter-related infection,cathter insufficiency,superior vena cava obstruction syndrome.Right venae jugularis interna intubation can evidently reduce the incidence of catheter-related infection,superior vena cava obstruction syndrome,and we also prove that catheter insufficiency has relevation to the location of the catheter,but not the time.Conclusion Location of catheter,resistant time of catheter and age are key risk factors of catheter-related infection,cathter insufficiency,superior vena cava obstruction syndrome.