腔隙性脑梗死和脑血栓形成患者颅内动脉狭窄的分布及特点
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Distribution of Intracranial Artery Stenosis in Patients with Lacuna Infarct and Cerebral Thrombosis
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    目的探讨腔隙性脑梗死和脑血栓形成患者颅内动脉狭窄的分布及特点。方法采用超高场强磁共振血管造影测定222例腔隙性脑梗死和228例脑血栓形成患者颅内动脉。结果222例腔隙性脑梗死患者颅内动脉狭窄112例(50.45%),其中在30~44岁、45~59岁和≥60岁三个年龄中狭窄发生率分别为16.67%、21.43%和60.12%。112例患者单发动脉狭窄38例(33.93%)和多发动脉狭窄74例(66.07%)。其中颅内动脉1级狭窄59.82%,2级狭窄30.36%,3级及以上狭窄9.82%。228脑血栓形成患者颅内动脉狭窄191例(83.77%),其中在30~44岁、45~59岁和≥60岁三个年龄中狭窄发生率分别为42.86%、80.77%和86.39%。191例患者单发动脉狭窄83例(43.46%)和多发动脉狭窄108例(56.54%)。其中颅内动脉1级狭窄34.56%,2级狭窄41.36%,3级及以上狭窄24.08%。两组30~44岁患者中以前循环单发颅内动脉狭窄为主,≥60岁组中以多发动脉狭窄多见,后循环动脉狭窄相对多见。结论脑血栓形成患者颅内动脉狭窄率明显高于腔隙性脑梗死患者。腔隙性脑梗死患者以颅内动脉1级狭窄为主,而脑血栓形成以2级以上狭窄为主。两组≥60岁患者随年龄增长多发动脉狭窄明显增加。

    Abstract:

    Aim To explore the distribution of intracranial artery stenosis in patients with lacuna infarct and cerebral thrombosis. Methods Magnetic resonance angiograghy was used to assess intracranial artery stenosis in 222 patients with lacuna infarct and 228 cerebral thrombosis. Results 112 subjects with intracranial artery stenosis were found in 222 patients with lacuna infarct(50.45%),being composed of 38 subjects with simplex artery stenosis and 74 subjects with complex artery stenosis.The prevalence of intracranial artery stenosis in the patients aged 30 to 44 years,45 to 59 years and 60 years and over was 16.67%,21.43% and 60.12%,respectively.The incidence of intracranial artery stenosis in grade 1,grade 2 and grade 3 and above was 59.82%,30.36% and 9.82%,respectively.The 191 subjects with intracranial artery stenosis were found in 228 patients with cerebral thrombosis(83.77%),being composed of 83 subjects with simplex artery stenosis and 108 subjects with complex artery stenosis.The prevalence of intracranial artery stenosis in the patients aged 30 to 44 years,45 to 59 years and 60 years and over was 42.86%,80.77% and 86.39%,respectively.The incidence of intracranial artery stenosis in grade 1,grade 2 and grade 3 and above was 34.56%,41.36%,24.08%,respectively.The proportion of simplex artery stenosis in anterior circulution was high in the patients aged 30 to 44 years with lacuna infarct and cerebral thrombosis.In contrast,the complex artery stenosis and the posterior circulation artery stenosis was frequently encounted in the patients aged 60 years and over. Conclusion The prevalence of intracranial artery stenosis with cerebral thrombosis was higher than that of lacuna infarct.The intracranial artery stenosis in grade 1 was the most frequently encounted in the patients with lacuna infarct and the stenosis in grade 2 and above was frequently encounted in the patients with cerebral thrombosis.The complex artery stenosis increased with the ages significantly in the patients aged 60 years and over.

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顾苏兵,林高平,施天明,王奕琪,张剑梅,陈桂花,丁忠祥.腔隙性脑梗死和脑血栓形成患者颅内动脉狭窄的分布及特点[J].中国动脉硬化杂志,2010,18(5):395~397.

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  • 收稿日期:2010-04-01
  • 最后修改日期:2010-05-05
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