冠心病及等危症住院患者踝臂指数及下肢外周动脉疾病患病率调查
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Mean Level of Ankle-Brachial Index and Prevalence of Peripheral Arterial Disease Among Inpatients with Equal-Risk to Coronary Heart Disease
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    摘要:

    目的了解冠心病及等危症住院患者踝臂指数分布情况及下肢外周动脉疾病患病情况。方法连续入选上海第十人民医院、首都医科大学附属北京同仁医院等32家医院符合条件的2509例住院患者(年龄≥45岁)为研究对象,测量每位患者踝臂指数的同时进行回顾性流行病学调查,踝臂指数≤0.9诊断为外周动脉疾病。结果冠心病及等危症住院患者踝臂指数均值为0.96±0.24,外周动脉疾病患病率为31.1%(95%CI为29.3%~33.0%);女性外周动脉疾病患病率明显高于男性(33.9%比28.8%,p<0.05);男女踝臂指数均值均随着年龄的增加而逐渐降低(p<0.0001),外周动脉疾病患病率随着年龄的增加而明显升高(p<0.0001);患者伴有高总胆固醇、高血压、糖尿病及缺血性脑卒中等危险因素具有较高的外周动脉疾病患病率和较低的踝臂指数均值;同时患有冠心病、糖尿病和缺血性脑卒中三种疾病的患者外周动脉疾病患病率达60.6%。结论我国≥45岁冠心病及等危症住院患者中外周动脉疾病普遍存在,是外周动脉疾病的高危人群,应引起临床医生的重视,并加强对危险因素的整合管理。

    Abstract:

    Aim To find the distribution of ankle-brachial index(ABI) and prevalence of peripheral arterial disease(PAD) among Chinese inpatients with equal-risk to coronary heart disease.Methods 2 509 inpatients with equal-risk to coronary heart disease were recruited from Shanghai and Beijing(age≥45 years).Associated factors and medical examinations were collected by a retrospective epidemiological survey.At one time,ABI was measured.PAD was diagnosed when the ABI was <0.9,inpatients with an ABI of >1.4 were excluded because of false negative rate.Results Mean level of ABI was 0.96±0.24 and prevalence of PAD was 31.1%(95%CI:29.3%~33.0%)in this study subjects.Prevalence of PAD in male and female were 33.9% and 28.8%(p<0.05),respectively.Prevalence of PAD was increased with advance age among men and women(p<0.0001),whereas mean level of ABI(p<0.0001).Inpatients with high level of total cholesterol,hypertension,ischemic stroke,and diabetes had higher prevalence of PAD in univariate analysis and lower level of ABI.Prevalence of PAD was up to 60.6% among inpatients combined with coronary heart disease,ischemic stroke,and diabetes.Conclusions PAD had universal occurrence in Chinese inpatients with equal-risk to coronary heart disease.Clinicians should attach importance to peripheral arterial disease and strengthen the management of risk factors of cardiovascular disease.

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郑黎强,余金明,李觉,孙兆青,孙英贤,胡大一.冠心病及等危症住院患者踝臂指数及下肢外周动脉疾病患病率调查[J].中国动脉硬化杂志,2007,15(11):857~860.

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  • 收稿日期:2007-09-10
  • 最后修改日期:2007-11-01
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