Aim To explore the predictive value of cardiac troponin Ⅰ(cTnⅠ) level on prognosis in patients with acute myocardial infarction (AMI)after angioplasty. Methods One hundred and two cases with ST elevation or new branch bond block (LBBB)who underwent consecutive angioplasty were divided into 2 groups: cTnⅠelevated group (64 cases)and cTnⅠnormal group (38 cases)according to the admission cTnⅠlevels. The clinical characteristics were observed and major cardiovascular events (MACE)at follow-up period of a mean 9.5±7.5 months were analysed. Results Compared with those in cTnⅠnormal group, the left ventricular ejection fractions (LVEF) decreased in cTnⅠelevated group (p<0.05); During clinical hospitalization, total rates of MACE (including overall incidences of congestive heart failure, non-fatal myocardial infarction and cardiac death) significantly increased in cTnⅠelevated group (32.8% vs 18.4%, p<0.05); in follow-up period, total rates of MACE (including overall incidences of non-fatal myocardial infarction, revascularization of target vessel and cardiac death) were significantly increased in cTnⅠelevated group (29.7% vs 15.8%, p<0.05). Conclusions cTnⅠlevel on admission was associated with adverse prognosis of short and long term in patients with AMI and is an independent predictor for total rates of MACE.