Aim To evaluate the clinical application of coro-uary artetiography (CAG) in diagnosis of coronary heart disease.Methods Selective coronary arteriography by means of multiple angled projecting cine-nuoroscopy was performed in 245 cases. The patients were divided into four groups, A: 101 mycardial infarction, B: 76 angina pectoris, C: 25 atypical angina pectoris, D: 24 non-coronary heart disease. 224 left cardioventricu lography can be reviewerl satisfactorilv in them. Results 164 CAG cases were abnormal. In group A the positive rate was 96. 1 %, and B 71. 1%,C 28. 9% respetively. In group D. no coronary le-sions can be found. 290 coronary artery branches were steootic. Among them 130 are in LAD. 80 LCX, 67 RCA, 13 LMCA successively. Pathologic manifesta-tions in left ventriculography are segrmental functional disorder or aneurysm of the left ventricular wall. The Positive rate in group A is 86. 5K, B 55. 2%, C 34-1 %, D 5% respectively.Conclusion CAG is still direct, more effcient ma-neuver to probe coronary heart disease.