Fifty-four cases with primary hyperten sive hypertrophy of left ventricle were randomly divided into two groups,one treated with slow-releaxing vera pamin,the other with nitredipine,The blood pressure,heart rate,cardiac function and thickness of left ventri cle were measured before and after treatment in both groups.In the group treated with slow-releaxing vera pamin,the blood pressure declined very significantly(P<0.01) ,heart rate declined (P<0.01),function of left ventricle improved (P<0.01)and hypertrophy of left ventricle reversed favourably(P<0.05).On the contrary only the blood pressure declined(P<0.01) and there were nothing improving in the other aspects in group treated with nitredipine (P>0.05).